首页/数据集/Botulinum neurotoxin subtype A6 cell binding domain in complex with GD1a ganglioside

Botulinum neurotoxin subtype A6 cell binding domain in complex with GD1a ganglioside

NIAID Data Ecosystem2026-05-02 收录

肉毒毒素结构生物学

神经节苷脂

数据链接：

https://www.rcsb.org/structure/8AGK 数据链接链接失效反馈

官方服务：

资源简介：

Botulinum neurotoxin subtype A6 cell binding domain in complex with GD1a ganglioside

应用场景：

创建时间：

2024-11-20

细胞膜探针结合动力学

神经节苷脂

Organized assembly or aggregation of sphingolipid-binding ligands, such as certain toxins and pathogens, has been suggested to increase binding affinity of the ligand to the cell membrane and cause me

NIAID Data Ecosystem50

Antibody Recognition of Cancer-Related Gangliosides and Their Mimics Investigated Using in silico Site Mapping

癌症免疫治疗靶点

神经节苷脂

Modified gangliosides may be overexpressed in certain types of cancer, thus, they are considered a valuable target in cancer immunotherapy. Structural knowledge of their interaction with antibodies is

Figshare2012-04-20 更新30

Amyloid Precursor Protein (APP) Mediated Regulation of Ganglioside Homeostasis Linking Alzheimer's Disease Pathology with Ganglioside Metabolism

阿尔茨海默病分子机制

神经节苷脂

Gangliosides are important players for controlling neuronal function and are directly involved in AD pathology. They are among the most potent stimulators of Aβ production, are enriched in amyloid pla

Figshare2016-01-19 更新20

GNPS - Sialidase NEU3 action on GM1 ganglioside is neuroprotective in GM1 Gangliosidosis

神经节苷脂

谱学定量分析

Three runs for each sample for quantitation (MS1 spectra only) which are dated 20230716. One run for each sample for identification with UVPD. Peak area was quantified using the Genesis algorithm in Q

NIAID Data Ecosystem40

SeviL, a GM1b/asialo-GM1 binding lectin

糖-蛋白质相互作用

神经节苷脂

SeviL, a GM1b/asialo-GM1 binding lectin

NIAID Data Ecosystem30