Mechanisms of letermovir breakthrough during the French Named Patient Program
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https://www.ncbi.nlm.nih.gov/sra/SRP234610
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资源简介：
Mechanisms of letermovir breakthrough during compassionate primary and secondary prophylaxis were analyzed in 4 patients. Of 3 absolute resistance cases 2 were associated with treatment interruption or low letermovir concentrations in blood. The 4th was not associated with resistance. NGS genotyping confirmed rapid emergence of resistant mutants, before 3 months.
创建时间：
2020-10-23
