Small molecule inhibitors of the LEDGF site of HIV type 1 integrase identified by fragment screening and structure based drug design Descriptor: 5-[[[2-[[(1S)-1-(4-METHOXYPHENYL)BUTYL]CARBAMOYL]PHENYL

Protein Data Bank Japan2023-12-20 更新40

Normalized decision matrix NM (BP Case).

艾滋病药物设计

拓扑指数分析

Topological indices are crucial tools for predicting the physicochemical and biological features of different drugs. They are numerical values obtained from the structure of chemical molecules. These

Figshare2025-01-17 更新30

Crystal Structure of wild-type HIV-1 Protease in Complex with MKP56

HIV-1蛋白酶

抗病毒药物设计

Crystal Structure of wild-type HIV-1 Protease in Complex with MKP56 Descriptor: 2-[(dichloroacetyl)amino]ethyl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl][(2S)-2-methylbutyl]amino}-1-phenylbutan

Protein Data Bank Japan2024-02-28 更新60

HIV-1 Reverse Transcriptase in Complex with TMC278

艾滋病药物设计

蛋白质-配体复合物结构

HIV-1 Reverse Transcriptase in Complex with TMC278

NIAID Data Ecosystem40