five

A model for detecting the effects of vibration on peripheral blood flow

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ICPSR2025-01-01 更新2026-04-16 收录
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Exposure to hand-transmitted vibration (HTV) has been shown to result in cold-induced vasoconstriction and a reduction in blood flow to the hands and fingers of workers. Occupational exposure to HTV can also induce a hypersensitivity of the sympathetic nervous system to various stimuli, which in turn can result in vasoconstriction of the peripheral blood vessels and blanching of the skin because of reductions in peripheral blood flow. The data presented were collected using an established animal model of vibration-induced white finger (Welcome et al. 2008) to determine if changes in blood flow induced by vibration exposure could be used as a biomarker for the development of vibration-induced peripheral vascular disease. Two separate experiments were done. In Experiment 1, changes in blood flow were measured in the ventral tail artery of the rat tail before and after a 4 h exposure to tail vibration (frequency 125 Hz, amplitude 5 g). These data were compared with those of animals that were restrained and had t
提供机构:
United States Department of Health and Human Services. Centers for Disease Control and Prevention. National Institute of Occupational Safety and Health
创建时间:
2025-01-01
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