Gene expression changes after loss of C/EBPα in transformed HSCs [CEBPA RNA-seq]
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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资源简介:
RNAseq characterization of gene expression changes 72 hours after genomic excision of Cebpa in murine hematopoietic progenitors from Cebpaf/f;CreER mice transformed by Hoxa9/Meis1. In the presence of tamoxifen (4OHT), Cre-ER localizes to the nucleus of cells allowing for excision of Cebpa and loss of C/EBPα protein levels. Loss of C/EBPα leads to a decrease in cellular proliferation.
提供机构:
Medimmune
创建时间:
2022-02-20



