Crystal Structure of PI5P4KIIAlpha complex with Volasertib
收藏Protein Data Bank Japan2023-10-18 更新2026-04-19 收录
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Crystal Structure of PI5P4KIIAlpha complex with Volasertib Descriptor: N-{trans-4-[4-(cyclopropylmethyl)piperazin-1-yl]cyclohexyl}-4-{[(7R)-7-ethyl-5-methyl-8-(1-methylethyl)-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxybenzamide, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, SULFATE ION Authors: Chen, S, Ha, Y. Deposit date: 2021-06-10 Release date: 2021-06-30 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Pharmacological inhibition of PI5P4K alpha / beta disrupts cell energy metabolism and selectively kills p53-null tumor cells. Proc.Natl.Acad.Sci.USA, 118, 2021
创建时间：
2021-06-10
