Protein expression levels of Myc and Pmp22 in the mouse model.

The protein expression levels of Myc and Pmp22 were measured in the nucleus and cytoplasm. The P-values were obtained for the following categories: Normal vs. N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN) (Nucleic Myc, P<0.001; Cytoplasmic Pmp22, P<0.001), BBN vs. BBN + nicotinamide (NC) (Nucleic Myc, P<0.001; Cytoplasmic Pmp22, P = 0.001), and Normal vs. BBN + NC (Nucleic Myc, P = 0.12; Cytoplasmic Pmp22, P = 0.42). The P-values were calculated by two sample t-tests to each comparison. When applying correlation test between nucleic Myc and cytoplasmic Pmp22, two molecules were strongly inversely correlated. (r = −0.83, P<0.001). Correlation test was carried out by Pearson correlation test. SD indicates standard deviation.