LpxC from P.aeruginosa with the inhibitor 6-(benzimidazol-1-yl)-5-[4-[2-[6-[(4-methylpiperazin-1-yl)methyl]-3-pyridyl]ethynyl]phenyl]pyridine-3-carbohydroxamic acid

LpxC from P.aeruginosa with the inhibitor 6-(benzimidazol-1-yl)-5-[4-[2-[6-[(4-methylpiperazin-1-yl)methyl]-3-pyridyl]ethynyl]phenyl]pyridine-3-carbohydroxamic acid Descriptor: 6-(1H-benzimidazol-1-yl)-N-hydroxy-5-[4-({6-[(4-methylpiperazin-1-yl)methyl]pyridin-3-yl}ethynyl)phenyl]pyridine-3-carboxamide, UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ZINC ION Authors: Olivier, N.B, Lahiri, S.D, Prince, D.B. Deposit date: 2014-01-22 Release date: 2014-09-24 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Overexpression of Pseudomonas aeruginosa LpxC in the Presence of an Inhibitor in an acrB Deletion Escherichia coli strain for Structural Studies Protein Express.Purif., 2014

来自铜绿假单胞菌（P. aeruginosa）的LpxC，其结合抑制剂6-(苯并咪唑-1-基)-5-[4-[2-[6-[(4-甲基哌嗪-1-基)甲基]-3-吡啶基]乙炔基]苯基]吡啶-3-碳羟肟酸。描述符：6-(1H-苯并咪唑-1-基)-N-羟基-5-[4-({6-[(4-甲基哌嗪-1-基)甲基]吡啶-3-基}乙炔基)苯基]吡啶-3-甲酰胺、UDP-3-O-[3-羟基肉豆蔻酰基]N-乙酰葡糖胺脱乙酰酶、锌离子（ZINC ION）。作者：Olivier, N.B.、Lahiri, S.D.、Prince, D.B.。提交日期：2014-01-22；发布日期：2014-09-24；最后修改日期：2024-02-28。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.06埃（Å）。引用文献：《在缺失acrB的大肠杆菌菌株中结合抑制剂过表达铜绿假单胞菌LpxC以开展结构研究》，发表于Protein Express.Purif.，2014年。