The detection of cytosolic viral nucleic acids via pattern-recognition receptors (PRRs) activates multiple signaling pathways, leading to the production of interferons (IFNs), which are essential for

Figshare2025-07-24 更新20

Data_Sheet_7_N6-methyladenosine modulation classes and immune microenvironment regulation in ischemic stroke.XLSX

缺血性卒中免疫微环境

m6A表观转录组学

N6-methyladenosine (m6A) modifications play an important role in the differentiation and regulation of immune cells. However, research on m6A in ischemic stroke (IS) is still in its infancy, and their

NIAID Data Ecosystem10

Widespread N6-methyladenosine-dependent RNA Structural Switches Regulate RNA-Protein Interactions

m6A表观转录组学

RNA-蛋白质相互作用

We show that N6-methyladenosine (m6A), the most abundant internal modification in mRNA/lncRNA with still poorly characterized function, alters RNA structure to facilitate the access of RBM for heterog

NIAID Data Ecosystem30

A novel RNA m6A modulator Zc3h13 plays an anchor role in facilitating nuclear RNA methylation and mouse embryonic stem cell self-renewal

m6A表观转录组学

胚胎干细胞自我更新

N6-methyladenosine (m6A) is an abundant modification in eukaryotic mRNA, regulating mRNA dynamics by influencing mRNA stability, splicing, export and translation. Recent studies discovered m6A methylt

NIAID Data Ecosystem10

A study of m6A modification controls the innate immune response to infection by targeting type I interferons

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