Downregulated proteins in <i>N. gonorrhoeae</i> biofilms listed by functional roles^a: Biofilm/Planktonic ratios expressed as log₂ values, 2-fold decrease (log₂ values ≤−1.000) measured in at least one Extract, and p-values <0.05.

aFunctional role assignments (both main and JCVI sub-roles) for the N. gonorrhoeae proteins were downloaded from the JCVI-CMR website. bAverage log2 values for biofilm/planktonic protein ratios. c(N) represents the number of measurements (biological replicates) averaged. dProtein with more than one functional role assignment provided (Main role/JCVI sub-role): NGO0639, Energy metabolism/Glycolysis/gluconeogenesis. eProtein functional role category tentatively assigned in the present study by orthology to an N. meningitidis protein (see Supplementary Table S6 for details).