Myeloid progenitor cells lacking p53 exhibit delayed upregulation of Puma, prolonged survival after cytokine deprivation. Mus musculus
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA121619
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资源简介：
We generated WT and p53-/- Factor Dependent Myeloid (FDM) cells and found that p53-/- cells were protected against IL-3 withdrawal. A survival advantage was also observed in untransformed p53-/- hematopoietic progenitor cells cultured in the presence or absence of cytokines. Array analysis was perfomed on RNA extracted from WT and p53-/- FDM cells. Overall design: Total RNA obtained from WT and p53-/- FDM cells cultured in the presence or absence of IL-3
创建时间：
2009-12-07
