Most frequent primary MOA assignments within meta-clade groups A:G.

Figshare2021-04-28 更新2026-04-28 收录

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https://figshare.com/articles/dataset/Most_frequent_primary_MOA_assignments_within_meta-clade_groups_A_G_/14508317 数据链接链接失效反馈

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Most frequent primary MOA assignments within meta-clade groups A:G.

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2021-04-28

Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes in Multiple Myeloma (MM) cell lines treated with DMSO and Indirubin-3’-monoxime (I3MO)

癌细胞转录组

药物作用机制

To determine what signaling pathways are affected by I3MO in MM cells, 5 MM cell lines including ANBL6, ANBL6 BR, ARP1, RPMI-8226, and U266, were cultured with DMSO or 5/10µM I3MO for 48 h. Total RNAs

NIAID Data Ecosystem60

Momordicine I Suppresses Glioma Growth by Promoting Apoptosis and Impairing Mitochondrial Oxidative Phosphorylation. Momordicine I Suppresses Glioma Growth by Promoting Apoptosis and Impairing Mitochondrial Oxidative Phosphorylation

神经胶质瘤治疗

药物作用机制

RNA microarray was performed from glioma cell LN229 and GBM8401 that were treated with Momordicine (10 microM) for 48hr in comparison to DMSO vehicle control Overall design: To study the growth inhibi

NIAID Data Ecosystem30

WP2435 - Quercetin and Nf-kB / AP-1 induced apoptosis - Homo sapiens

细胞信号通路

药物作用机制

Quercetin is a flavonoid that is widely distributed in nature. In this pathway, its dual nature is depicted. On the one hand, it is capable of exerting anti-oxidant and anti-inflammatory effects by in

NIAID Data Ecosystem10

Inhibitory Effects of Vinpocetine on the Progression of Atherosclerosis Are Mediated by Akt/NF-κB Dependent Mechanisms in apoE -/- Mice

动脉粥样硬化治疗

药物作用机制

Background Recent studies have found additional roles for vinpocetine, a potent phosphodiesterase type I inhibitor, in anti-proliferation and anti-inflammation of vascular smooth muscle cells and canc

NIAID Data Ecosystem60

Table S5

SARS-CoV-2基因分析

药物作用机制

Table S5. Differentially expressed genes identified by RNAseq in sample comparisons highlighting the effect of SARS-CoV-2. Entrez GeneID NCBI unique gene identifier Gene Symbol Common abbreviated gene

Figshare2022-12-05 更新10

Most frequent primary MOA assignments within meta-clade groups A:G.

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