Genome wide expression analysis of Caenorhabditis elegans cdk-8(tm1238) null mutants (vs. WT N2 worms)
收藏Alliance of Genome Resources2026-08-01 收录
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CDK-8 is the catalytic subunit of the Mediator complex and is known to regulate specific gene programs in yeast and in cultured mammalian cells; because no study has yet identified CDK-8 regulated genes in an in vivo animal model, we performed genome wide expression profiling on cdk-8 null mutant C. elegans worms to identify CDK-8 regulated genes and developmental and/or physiological gene programs.
