Neurons harbor high levels of endogenous single strand DNA breaks (SSBs) that are targeted to neuronal enhancers and correlate with marks of DNA demethylation. To determine the source of SSBs at neuro
Cyclobutane pyrimidine dimers (CPD), as a common DNA damage caused by UV radiation, often lead to disastrous diseases. Here, we identified a photolyase from Arthrospira platensis (designated as Ap-phr
Bloom syndrome protein (BLM) is one of five human RecQ helicases which maintain genomic stability. Interaction of BLM with replication protein A (RPA) stimulates the DNA unwinding ability of BLM. The
