We used RNA-seq to investigate transcriptional changes in human islet grafts that were treated in vivo with tacrolimus or sirolimus. We show that this treatment induces broad transcriptional dysregula
Eosinophils were isolated from the lungs of mice that were resting naïve or 7 or 30 days post-transplant with costimulatory blockade Overall design: Lungs of 3 to 5 mice were pooled per sample. Lung
HLA Class II Haplotype Frequency Distributions (for 99% haplotypes per population) and HLA Class II Simulated Populations (Genotype level information for sample sizes of 1000, 5000, 10000 simulated in
Transcriptome analysis of murine T cells pre- and post-transplant. Overall design: Sorted CD4 and CD8 splenic T cells where evaluated by RNA-seq either at the time of allogeneic transplant or 14 days
In contrast to non-nucleated ABO-incompatible red cells, which from a HLA-compatible donor are transfused to a blood group O(H) recipient and undergo immediate destruction, a nucleated, metabolic acti