Embryo-derived chemokine CXCL12 enhances the pregnancy outcome via improved endometrial receptivity

Intrauterine infusion of CXCL12 has a beneficial effect on endometrial angiogenesis by recontruction of endometrial vasculature and improvement of endometrial receptivity Overall design: As a non-invasive treatment strategy, CXCL12 was infused into one side of mouse uterine horns and saline was infused into the other side of horns for the control (N=28). Assessment of CXCL12 impact on the endometrium at day3 and day8.