The role of PARP-1 in estrogen-dependent transcription
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2021-10-13
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NAD+ Analog-sensitive PARPs Reveal a Role for PARP-1 in Transcription Elongation
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Condensin I Recruitment to Base Damage-Enriched DNA Lesions Is Modulated by PARP1
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A Versatile Toolbox Reveals XRCC1 Deficiency–Driven Reshaping of the PARP1 Mono-ADP-Ribosylation Wave
ADP-ribosylation has long been recognized as a key regulator of essential signaling pathways, including the DNA damage response. However, only recent and ongoing technological advances are beginning
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PARP1 regulates VSMC phenotypic switch and neointima via Myocardin. PARP1 regulates VSMC phenotypic switch and neointima via Myocardin
We applied the transcriptome profiling (RNA-seq) for high-throughput profiling of genes changes in VSMC dedifferentiation. Rat primary VSMCs were divided into 3 groups, control, PDGF-BB, PDGF-BB+PJ34,
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Mitochondrial PARP1 Regulates NAD+-dependent Poly ADP-ribosylation on Mitochondrial Nucleoids. Mitochondrial PARP1 Regulates NAD+-dependent Poly ADP-ribosylation on Mitochondrial Nucleoids
Poly ADP-ribose (PAR) polymerases (PARPs) play fundamental roles in multiple DNA damage recognition and repair pathways. Persistent nuclear PARP activation causes cellular NAD+ depletion and exacerbat
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