Plasma and faecal metabolomic data, and intestinal microbial communities of mice exposed to cold temperature or RT.

Mice were allocated into three groups: the room temperature (RT) group maintained at 24°C; the cold group exposed to 4°C for four hours daily, with the remaining time spent at RT; and the continuous cold (CC) group kept in a sustained cold (4°C) environment. After four-week intervention, mice were anaesthetized, and plasma and faecal samples were harvested for untargeted metabolomics. Faecal samples were also collected for shotgun metagenomics.