Additional file 6 of SRSF3 and SRSF7 modulate 3′UTR length through suppression or activation of proximal polyadenylation sites and regulation of CFIm levels
We identified a germline heterozygous loss-of-function mutation in ZCCHC8, an RNA exosome targeting component, in a family with autosomal dominant pulmonary fibrosis and telomerase RNA insufficiency.
Additional file 7: Table S6. List of PASs identified by Sierra in six PBMC scRNA-seq datasets from 10x Genomics. Sierra-identified exonic and intronic PASs in each PBMC dataset were individually liste
scTail is a stepwise computational method to identify polyadenylation site at single cell resolution. Here, we upload the test file of scTail, gene and PAS profile of human intestinal, mouse forelimb
scTail is a stepwise computational method to identify polyadenylation site at single cell resolution. Here, we upload the test file of scTail, gene and PAS profile of human intestinal, mouse forelimb
The stability, localization and translation of mammalian mRNAs are largely determined by sequences in the 3' untranslated region (UTR). Here, we describe a conserved program of increased upstream poly