遇见数据集

Raw data supporting "Candida auris infected zebrafish larvae gives an insight on the virulence factor of the C. auris with aggregate forming phenotype"

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Zenodo2025-05-20 更新2026-05-26 收录
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This dataset contains the raw data and figures associated with a study investigating the virulence characteristics of various Candida auris strains using the zebrafish infection model. Specifically, it includes: Figure 1: Survival curves of zebrafish embryos infected with different C. auris strains over a 96-hour period, compared to a mock control. Figure 2: Quantitative analysis of fungal burden (CFU/mL) within zebrafish embryos infected with five C. auris strains at multiple timepoints. Figure 3: Assessment of biofilm formation by Candida species. (A) Metabolic activity measured via XTT assay at 24 and 48 hours. (B) Biomass quantification using crystal violet staining at the same timepoints. C. albicans ATCC 90028 was used as a positive control. Figure 7: Evaluation of chitin content in the cell walls of C. auris strains through Calcofluor White staining and confocal microscopy, including quantification of fluorescence intensity. Supplementary Table 1: Enzymatic activity profiles (phospholipase, proteinase, hemolysin) of five C. auris strains, compared with C. albicans ATCC 90028, highlighting their virulence-associated hydrolytic enzyme production. All experiments were independently performed in biological triplicates. The dataset supports the findings presented in the manuscript submitted to Virulence and may be useful for researchers studying fungal pathogenesis and host-pathogen interactions in vivo.

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Zenodo
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2025-05-20
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