Source Data for Nanopore sensing with DNA nanostructures reveals Guide-Intrinsic Mismatch Tolerance of CRISPR/dCas9
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This is the source data for Nanopore sensing with DNA nanostructures reveals Guide-Intrinsic Mismatch Tolerance of CRISPR/dCas9 in Nature Biomedical Engineering. The data was generated by mixing a DNA nanostructure with dCas9 and measuring the change in current generated from translocation in solid-state nanopores. Data is originally in TDMS format (which can be given upon request) and then converted from TDMS to hdf5 using https://bitbucket.org/nikaer/nanopyre/src/master/ - from this translocationfinder is used which writes files from TDMS (labview) to hdf5. Processing and further data analysis from the hdf5 is done using https://github.com/sarahsandler/nanopro. TDMS files are from labview, however there is a nptdms software which can be used to read them into python. Please see the manuscript for more details.
提供机构:
Apollo - University of Cambridge Repository
创建时间:
2023-05-04



