Guts collected from honeybees(Apis mellifera) 16S rRNA V3-4 amplicons Raw sequence reads

In this study, we established a consortium based on phylogeny analysis, the Core-20 community, consisting of 20 strains isolated from the honeybee intestine that provide colonization resistance against H. alvei. Interestingly, the higher complex and biodiversity community displays advantages in promoting the expression of regulators and AMPs of the immune system. The comparative genomic analysis revealed that the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS system) could potentially be involved in manipulating immune responses. In addition, we transmitted the Core-20 community for four passages and we found that the Core-20 could colonize steadily.