Systems-based approaches enable the development of industrial yeast strains with improved phenotypes. Saccharomyces cerevisiae AWRI1631

Although metabolic engineering approaches have benefited the development of industrial strains enormously, they are often only partially successful, such that additional rounds of modification are generally needed to ensure microbial strains meet all the requirements of a particular process. Systems biology approaches can aid in yeast design providing an integral view of yeast physiology and help identifying targets for modification.