Responses of human MAIT cells to CA7S
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE228498
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To investigate the effect of cholic acid sulfate to MAIT cells, PBMCs were stimulated with 5-OP-RU and CA7S and scRNA sequencing was performed. Inflammatory genes were induced by 5-OP-RU, while wound healing related genes were inducesed by CA7S. This analysis showed that cholic acid sulfate may contributes to maintenance of MAIT cells. PBMCs were unstimulated or stimulated with 5-OP-RU or with CA7S overnight. CD161+MR1-5-OP-RU tetramer+ cells were sorted and analyzed by single-cell TCR- and RNA-seq.
创建时间：
2025-06-06
