The University of California San Diego annotated post-treatment high-grade glioma multimodal MRI dataset (UCSD-PTGBM)

While there is a growing number of publicly available pre-operative MRI datasets for high-grade gliomas, very few post-operative datasets are available. Here we present the University of California San Diego post-operative high-grade glioma multimodal MRI (UCSD-PTGBM) dataset. The UCSD-PTGBM dataset includes 243 timepoints from 178 subjects (mean age 56 +/- 13 years [std], 116 men, 62 women) with histopathologically-proven high-grade gliomas who were imaged with an advanced brain tumor protocol on 3 Tesla MRI scanners. Sequences include standard 3D imaging, as well as multishell diffusion and perfusion imaging techniques (ASL and DSC), and neuroradiologist approved voxelwise tumor segmentations. The dataset also includes IDH mutation status and MGMT promoter methylation status, as well as overall survival and progression free survival information for several cases. We hope that researchers around the world will use these data to continue to improve analysis of post-operative MRI on high grade glioma patients.

尽管目前公开可用的高级别胶质瘤术前磁共振成像（MRI）数据集数量日益增多，但术后可用的同类数据集却极为匮乏。本文特此发布加利福尼亚大学圣地亚哥分校术后高级别胶质瘤多模态磁共振成像（UCSD-PTGBM）数据集。该数据集涵盖178名受试者的243个时间点数据：受试者平均年龄为56±13岁（标准差），其中男性116例、女性62例；所有受试者均经组织病理学确诊为高级别胶质瘤，并在3特斯拉磁共振成像扫描仪上采用先进脑肿瘤成像协议完成扫描。成像序列包含标准三维成像、多壳层扩散成像与灌注成像技术（动脉自旋标记（ASL）、动态磁敏感对比成像（DSC）），同时包含经神经放射学家认可的逐体素肿瘤分割结果。此外，该数据集还收录了部分病例的异柠檬酸脱氢酶（IDH）突变状态、O6-甲基鸟嘌呤-DNA甲基转移酶（MGMT）启动子甲基化状态，以及总生存期与无进展生存期信息。我们期望全球研究者能够利用本数据集，进一步优化高级别胶质瘤患者术后磁共振成像的分析工作。