Proinflammatory IgG Fc structures in patients with severe COVID-19
收藏DataCite Commons2022-12-21 更新2025-04-16 收录
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https://www.immport.org/shared/study/SDY1781
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资源简介：
Patients with severe COVID-19 produced a unique serologic signature, including an increased likelihood of IgG1 with afucosylated Fc glycans. Fc afucosylation enhanced production of inflammatory cytokines by monocytes, including interleukin-6 and tumor necrosis factor. These results show that disease severity in COVID-19 correlates with the presence of proinflammatory IgG Fc structures, including afucosylated IgG1.
提供机构：
ImmPort
创建时间：
2022-03-11
