HDMX (14-111; C17S) COMPLEXED WITH COMPOUND 14 AT 2.4A: Structural states of Hdm2 and HdmX: X-ray elucidation of adaptations and binding interactions for different chemical compound classes

HDMX (14-111; C17S) COMPLEXED WITH COMPOUND 14 AT 2.4A: Structural states of Hdm2 and HdmX: X-ray elucidation of adaptations and binding interactions for different chemical compound classes Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 3-[[6-chloranyl-3-[3-[(1~{S})-1-(2,4-dichlorophenyl)ethyl]-5-phenyl-imidazol-4-yl]-1~{H}-indol-2-yl]carbonylamino]-4-[4-(2-oxidanylidene-1,3-oxazinan-3-yl)piperidin-1-yl]benzoic acid, Protein Mdm4, ... Authors: Kallen, J. Deposit date: 2018-12-18 Release date: 2019-05-15 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural States of Hdm2 and HdmX: X-ray Elucidation of Adaptations and Binding Interactions for Different Chemical Compound Classes. Chemmedchem, 14, 2019

分辨率2.4埃的与化合物14结合的HDMX（14-111；C17S）复合物：Hdm2与HdmX的结构状态——不同类别化学化合物的适配模式与结合相互作用的X射线解析
描述项：1,4,7,10,13,16-六氧杂环十八烷，3-[[6-氯-3-[3-[(1S)-1-(2,4-二氯苯基)乙基]-5-苯基-1H-咪唑-4-基]-1H-吲哚-2-基]羰基氨基]-4-[4-(2-氧代-1,3-恶嗪烷-3-基)哌啶-1-基]苯甲酸，蛋白Mdm4（Protein Mdm4）……
作者：Kallen, J.
提交日期：2018年12月18日
发布日期：2019年5月15日
最后修改日期：2024年1月24日
实验方法：X射线衍射（分辨率2.4埃）
引用文献：Structural States of Hdm2 and HdmX: X-ray Elucidation of Adaptations and Binding Interactions for Different Chemical Compound Classes. Chemmedchem, 14, 2019