Naming conventions and hydrophobicity density requirements for FOD model classes.

Example levels of Q quantiles are visualized in Fig 4. One reads as follows: if hydrophobicity of an amino acid is above Q3 for theory and observation, then it is assumed to be highly hydrophobic and assigned to both H+2 and H+1 classes. If values of both theory and observation are below second quantile Q2 of their respected distributions, such residue is marked as hydrophilic and assigned to H–1 class. Residues with hydrophobicity characteristics not matching any of the criteria, such as those with Ht > tQ2 and Ho 2 (or vice versa), are assumed to be discordant with the FOD model and are left unassigned.Naming conventions and hydrophobicity density requirements for FOD model classes.