官方服务：
资源简介：
Whole Exome Sequencing Data for 10 patients for treatment with the ICI NivolumabEGA dataset EGAD00001011117
应用场景：
创建时间：
2023-07-28
相关数据集
Panicum virgatum SWAG1-095 Exome Capture exome
Switchgrass diversity analysis via exome sequencing
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EGAS00001000069-sc-20110610 - samples
Determination of the molecular nature of the Vel blood group by exome sequencingEGA dataset EGAD00001000025
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Targeted sequencing of IDH1 and IDH2 genes was performed using bone marrow specimens from matched diagnosis and relapsed AML patients with IDH baseline mutation before or after IDHmut inhibitor treatment. gDNA was extracted from the bone marrow clot sections using the QuickExtract FFPE DNA extraction kit (Epicenter Biotechnologies) following the manufacturer's instructions. The exon sequences of IDH1 and IDH2 genes were PCR amplified. The DNA fragments for each exon were purified with QIAquick spin columns (Qiagen), mixed at equal molarity, and fragmented using Covaris acoustic shearing following the manufacturer’s instructions. Sonicated DNA was processed for library generation using NEBNext Ultra II DNA Kits (New England Biolabs) following the manufacturer’s protocol. Libraries with different index sequences were quantified, pooled, and sequenced on an Illumina Nextseq500 system using the 75bp high output sequencing kit.. Targeted sequencing of IDH1 and IDH2 genes in AML samples
Acquired resistance to allosteric inhibition of cancer-associated IDH mutations has been described through mutations to restore the production of oncometabolite R-2HG, yet the complete repertoire of I
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ena-DATASET-INSERM-07-12-2017-12:46:35:359-402 - samples
One sample of human genomic DNA. DNA extracted from whole blood. Reads obtained using an exome enrichment kit (Truseq, Illumina) and sequencing of 100bp paired-end reads on a HiSeq 2500 sequencing sy
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Panicum virgatum exome capture - WS08-R3-5. Panicum virgatum cultivar:WS08-R3
Switchgrass diversity analysis via exome sequencing
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