PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P07B10 from the F2X-Universal Library

PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P07B10 from the F2X-Universal Library Descriptor: A1 cistron-splicing factor AAR2, N-(2-methylpentan-2-yl)-1H-pyrazole-3-carboxamide, Pre-mRNA-splicing factor 8 Authors: Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S. Deposit date: 2022-08-26 Release date: 2022-11-02 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites. J.Med.Chem., 65, 2022

PanDDA分析小组提交数据集——Aar2/RNaseH与F2X通用文库来源的片段P07B10形成的复合物。数据集说明：A1顺反子剪接因子AAR2、N-(2-甲基戊-2-基)-1H-吡唑-3-甲酰胺、前mRNA剪接因子8。作者：Barthel, T、Wollenhaupt, J、Lima, G.M.A、Wahl, M.C、Weiss, M.S。提交日期：2022-08-26；发布日期：2022-11-02；最后更新日期：2024-05-22。实验方法：X射线衍射（1.54 Å，埃）。引用文献：《大规模晶体学片段筛选加速化合物优化并鉴定潜在蛋白质-蛋白质相互作用位点》，《药物化学杂志（J.Med.Chem.）》，第65卷，2022年。