Crystal structure of influenza A neuraminidase N3 complexed with oseltamivir

Crystal structure of influenza A neuraminidase N3 complexed with oseltamivir Descriptor: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... Authors: Li, Q, Qi, J, Vavricka, C.J, Gao, G.F. Deposit date: 2012-11-15 Release date: 2013-11-06 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Functional and structural analysis of influenza virus neuraminidase N3 offers further insight into the mechanisms of oseltamivir resistance. J.Virol., 87, 2013

甲型流感病毒神经氨酸酶（neuraminidase）N3与奥司他韦（oseltamivir）复合物的晶体结构
描述：(3R,4R,5S)-4-(乙酰氨基)-5-氨基-3-(戊-3-氧基)环己-1-烯-1-羧酸、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-[α-L-岩藻吡喃糖-(1→6)]2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、钙离子（CALCIUM ION）……
作者：李晴（Li, Q）、齐建（Qi, J）、Vavricka C.J.、高福（Gao, G.F.）
存放日期：2012-11-15
发布日期：2013-11-06
最后修改日期：2024-11-20
实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.2埃（Å）
引用文献：流感病毒神经氨酸酶N3的功能与结构分析为奥司他韦耐药机制提供进一步见解。J.Virol., 87, 2013