Differential expression patterns separating breast cancer patient from control samples.

Differential expression testing for eight miRNAs in breast cancer patients (15) and controls (26) that showed some evidence of differential expression across quantile, RPKM and TMM normalisation methods. Welch t-tests for differential expression using RPKM values, upper quantile normalised rates and TMM normalised levels all supported lower miR-320a and miR-140 expression in breast cancer patients. The two-tailed p-values were Benjamini-Hochberg corrected to adjust for multiple testing and those with pDifferential expression patterns separating breast cancer patient from control samples.