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Epigenetic reprogramming in the mammalian embryo: struggle of the clones

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PubMed Central2002-01-29 更新2026-05-25 收录
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During preimplantation development in mammals, distinct epigenetic marks on oocyte and sperm DNA are remodeled to an embryonic pattern. A recent study examining global methylation of repetitive elements in various mammals showed that the reprogramming that occurs during normal preimplantation development is aberrant in cloned embryos.

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BMC
创建时间:
2002-01-29
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