Additional file 1: Tables S1-S9. of Assessment of piRNA biogenesis and function in testicular germ cell tumors and their precursor germ cell neoplasia in situ
In this study, we generated zebrafish pld6 knockouts and found that the pld6-null mutants developed as infertile males, with testes containing no germ cells. Pld6 is considered to be a candidate ribon
Animal germ cells produce PIWI-interacting RNAs (piRNAs), small silencing RNAs that suppress transposons and enable gamete maturation. Mammalian transposon-silencing piRNAs accumulate early in spermat
Adenosine Deaminase Domain Containing 2 (ADAD2) is a testis-specific protein composed of a double-stranded RNA binding domain and a non-catalytic adenosine deaminase domain. A recent study showed that
Piwi proteins are important for germ cell development and function in almost all animals studied thus far. These proteins are guided to specific targets, such as transposable elements, by small guide
