Comprehensive analysis of differentially expressed miRNAs in mice with kidney injury induced by chronic intermittent hypoxia

In this study, the altered miRNA profiles in a chronic intermittent hypoxia (CIH) mouse model were investigated, aiming to provide novel clues for delineating the underlying mechanisms of OSA-induced kidney injury. A CIH mouse model was established. miRNA microarray was then applied to profile miRNA expression in kidney samples from CIH groups and controls.