List of differential metabolites in brain tissues and urine in EPM group relative to controls, and aroma-EPM group relative to controls.

Note: 1Variable importance in the projection (VIP) was obtained from OPLS-DA model with a threshold of 1.0;
2fold change (FC) was obtained by comparing those metabolites in EPM group to control group;
3p values were calculated from Student’s t test;
4Adjusted for multiple testing with FDR control [18];
5FC was obtained by comparing those metabolites in aroma-EPM group to control group. FC with a value >1 indicates a relatively higher concentration present in EPM group or aroma-EPM group while a value <1 means a relatively lower concentration as compared to the controls.