Ashitaba in the management of Nonalcoholic Fatty Liver Disease

NIAID Data Ecosystem2026-05-01 收录

药物机制研究

疾病模型转录组学

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https://www.ncbi.nlm.nih.gov/sra/SRP450337 数据链接链接失效反馈

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资源简介：

NAFLD established mouse model was treated with or without Ashitaba, and the underlying mechanism was explored, using transcriptomics.

创建时间：

2023-10-11

Effect of Disulfiram on T cell activation

T细胞免疫调节

药物机制研究

To determine the effect of DSF on T cell activation ,we treated T cells with DSF and analyzed their functions. Comparative gene expression profiling analysis of RNA-seq for T cells after treated with

NIAID Data Ecosystem60

Integrated omics profiling reveals FOXA1 and Ku70/Ku80 as the direct target of ivermectin for prostate carcinogenic inhibition

前列腺癌靶向治疗

药物机制研究

Here, we show that ivermectin suppress prostate cancer progression by inhibiting AR signaling pathway and attenuate cellular DNA damage repair capacity. We applied an integrated omics profiling includ

NIAID Data Ecosystem60

Single-cell RNA sequencing analysis of iPSC-derived motor neurons from an ALS patient carrying ATXN2 intermediate repeat expansions and a healthy control

疾病模型转录组学

单细胞RNA测序

Intermediate-length repeat expansions in ATAXIN-2 (ATXN2) are a strong genetic risk factor for amyotrophic lateral sclerosis (ALS). At the molecular level, ATXN2 intermediate expansions enhance TDP-43

NIAID Data Ecosystem50

Top three gene ontology biological processes resulting from the analysis of differential regulated genes between antioxidant drugs and the respective solvent controls.

基因本体富集分析

药物机制研究

This analysis was performed using the DAVID program (see MM). Count indicates the number of genes belonging to the indicated gene ontology biological processes that we found regulated by a factor 2; %

NIAID Data Ecosystem60

Gene expression signatures in oridonin-treated WT and R878H hematopoietic stem cells. Gene expression signatures in oridonin-treated WT and R878H hematopoietic stem cells

药物机制研究

干细胞生物学

Analysis of WT-Ctl v.s. WT-Ori and R878H-Ctl v.s. R878H-Ori hematopoietic stem cell (lineage-, c-kit+ Sca-1+ CD150+, CD34-). The four population of hematopoietic stem cell (HSC) were purified from the

NIAID Data Ecosystem60

Ashitaba in the management of Nonalcoholic Fatty Liver Disease

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