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Application of a Raney-Cobalt-Mediated Tandem Reductive Cyclization Protocol to Total Syntheses of the <i>Aspidosperma</i> Alkaloids (±)-Limaspermidine and (±)-1-Acetylaspidoalbidine

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NIAID Data Ecosystem2026-03-07 收录
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The racemic modification of the Aspidosperma alkaloid limaspermidine (1) has been prepared in ten steps including one involving a Raney-cobalt-mediated tandem reductive cyclization of nitrile 8 to give the tetracyclic system 9b. Compound (±)-1 has been converted over two steps into (±)-1-acetylaspidoalbidine [(±)-13].

创建时间:
2016-02-20
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