Possible Model for Viral Gene Expression in Nonpermissive Cells Possible Model for Viral Gene Expression in Nonpermissive Cells

Contributor(s): University of California, San Francisco. Archives and Special Collections. Harold E. Varmus Papers UCSF Publication: Produced: [1978] Language(s): English Format: Still image Subject(s): Avian Sarcoma Viruses Genre(s): Archival Materials Slides (photographs) Charts (graphic documents) Abstract: This schematic drawing pictures how the genes of a transforming (cancer-causing) virus may be read, or expressed, by the infected cell's genetic machinery. The machinery includes messenger RNA (mRNA) and protein-producing structures called ribosomes. The cell type here is non-permissive, meaning a type or species of cell in which a particular virus cannot complete its replication cycle. The transforming protein--one that stimulates expression of genes controlling cell division, leading to cancerous growth--is produced, but no copies of the virus itself are made or released from the cell. Copyright: This item may be under copyright protection; contact the copyright owner for permission before re-use. Extent: 1 pages NLM Unique ID: 101584926X124 (See in Profiles in Science) Profiles in Science ID: MVBBJF Permanent Link: http://resource.nlm.nih.gov/101584926X124 Archival Collection: The Harold Varmus Papers (Profiles in Science)