Additional file 1 of Comparative analysis of hippocampal extracellular space uncovers widely altered peptidome upon epileptic seizure in urethane-anaesthetized rats

Additional file 1: Table S1. List of detected peptides in microdialysate samples. Peptide sequences, positions, Uniprot accession numbers, protein names, and normalized abundances are shown. (Norm ab: normalized abundance; 4Ap: 4-AP treated samples; ctrl: control samples). Table S2. List of significantly altered peptides upon 4-AP treatment (paired t-test, adjusted P-value < 0.05). Peptide sequences, positions, Uniprot accession numbers, gene symbols, and protein names are shown. Table S3. List of peptides that are detected in at least 9 of the 4-AP treated samples and not more than 2 of the control samples upon 4-AP treatment. Peptide sequences, positions, modifications, Uniprot accession numbers, gene symbols, and normalized abundances (Norm ab) are shown. (4Ap: 4-AP treated samples; ctrl: control samples). Table S4. Enrichment analysis on upregulated proteins. (Analysis was carried out by g:Profiler (version e106_eg53_p16_65fcd97) g:GOSt online tool with the background of Rattus norvegicus genome). Table S5. Enrichment analysis on downregulated proteins. (Analysis was carried out by g:Profiler (version e106_eg53_p16_65fcd97) g:GOSt online tool with the background of Rattus norvegicus genome). Table S6. Functional categories of proteins that had significantly altered peptides in the microdialysate.