Crystal structure of human apoptosis signal-regulating kinase 1 (ASK1) with imidazopyridine inhibitor
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Crystal structure of human apoptosis signal-regulating kinase 1 (ASK1) with imidazopyridine inhibitor Descriptor: 4-tert-butyl-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide, Mitogen-activated protein kinase kinase kinase 5 Authors: Terao, Y, Suzuki, H, Yoshikawa, M, Yashiro, H, Takekawa, S, Fujitani, Y, Okada, K, Inoue, Y, Yamamoto, Y, Nakagawa, H, Yao, S, Kawamoto, T, Uchikawa, O. Deposit date: 2012-08-06 Release date: 2012-10-31 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Design and biological evaluation of imidazo[1,2-a]pyridines as novel and potent ASK1 inhibitors. Bioorg. Med. Chem. Lett., 22, 2012
人类凋亡信号调节激酶1（ASK1）与咪唑并吡啶类抑制剂的共晶晶体结构
描述符：4-叔丁基-N-[6-(1H-咪唑-1-基)咪唑并[1,2-a]吡啶-2-基]苯甲酰胺，丝裂原活化蛋白激酶激酶激酶5（Mitogen-activated protein kinase kinase kinase 5）
作者：Terao Y、Suzuki H、Yoshikawa M、Yashiro H、Takekawa S、Fujitani Y、Okada K、Inoue Y、Yamamoto Y、Nakagawa H、Yao S、Kawamoto T、Uchikawa O
入库日期：2012-08-06
发布日期：2012-10-31
最后修改日期：2024-03-20
实验方法：X射线衍射（分辨率2.4埃）
引用文献：咪唑并[1,2-a]吡啶类新型强效ASK1抑制剂的设计与生物学评价. Bioorg. Med. Chem. Lett., 22, 2012
创建时间：
2012-08-06
