Hazard ratios (95% confidence intervals) for developing type 2 diabetes by weighted quartile of lactate concentrations.

Model 1: Age, gender, race, ARIC center, education.
Model 2: Model 1+ diagnosis of hypertension, prevalent coronary heart disease, smoking status, leisure index, parental history of diabetes.
Model 3: Model 2+ body mass index, waist circumference.
Model 4: Model 3+ log10 triglycerides, low density lipoprotein cholesterol, high density lipoprotein cholesterol.
Model 5a: Model 4+ fasting glucose.
Model 5b: Model 4+ log10 fasting insulin.
Model 5c: Model 4+ fasting glucose and log10 fasting insulin.
*P-value for trend evaluated using an ordinal variable based on the median lactate in each quartile.