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Urinary Cell Transcriptomics and Acute Rejection in Human Kidney Allografts

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NIAID Data Ecosystem2026-03-14 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP238911
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资源简介:
RNA-sequencing (RNA-Seq) is a precise tool to analyze global transcriptional changes, develop biomarkers, and decipher pathogenic mechanisms. We performed RNA-Seq of urinary cells to investigate gene expression patterns and pathways and whether urinary cell mRNA transcriptional profiles are enriched for biopsy transcriptional profiles. Overall design: We performed RNA-Seq of 57 urinary cell pellets of kidney allograft recipients obtained at the time of biopsy diagnosis of T cell mediated rejection (N=22), antibody mediated rejection (N=8), or Normal/nonspecific changes/no rejection (N=27)
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2023-01-11
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