It is now widely known that C-X3-C motif ligand 1 (CX3CL1) plays an essential part in the process of regulating pro-inflammatory cells migration across a wide range of inflammatory disorders, includin

NIAID Data Ecosystem00

CRISPR screening reveals targets to reprogram long-lived effector CD8+ T cells for cancer therapy [scRNA-seq]

肿瘤免疫治疗

T细胞编程

CD8+ T cells can be reprogrammed for better persistence and robust effector function in TME. By performing an in vivo pooled CRISPR-Cas9 mutagenesis screening of metabolism-associated factors, we iden

NIAID Data Ecosystem00

Genetically engineered superantigens as tolerable antitumor agents

肿瘤免疫治疗

超抗原工程

Superantigens (SAg) are a family of bacterial and viral proteins with strong immunostimulatory properties. SAg bound to major histocompatibility complex (MHC) class II molecules activate a high freque

PubMed Central1997-03-18 更新10

CyTOF data of MC38 tumor-bearing mice treated with aPD-1-mEry

肿瘤免疫治疗

CyTOF免疫细胞分析

Splenocytes were isolated from MC38 tumor-bearing C57BL/6-hPD-1 mice receiving 2 treatments of IgG4-mEry, αPD-1, or αPD-1-mEry.

NIAID Data Ecosystem00