The metabolic domestication syndrome of budding yeast

For a detailed description about the metabolomic measurements, see the following publication: https://doi.org/10.1073/pnas.2313354121

-ALL_AA.zip file: raw LC-MS files of amino acid measurements

-All_FIA.zip file: raw LC-MS files containing untargeted metabolome data

-All_TCA_cycle.zip file: raw LC-MS files of TCA cycle intemediate measurements

The following files contain data in MetaboLights like format:

-a_MTBLS9200_FIA-MS_negative__metabolite_profiling-1.txt pairing between sample names and filenames in untargeted metabolome profiling

-a_MTBLS9200_LC-MS_alternating_hilic_metabolite_profiling.txt pairing between sample names and filenames in Amino acid level determination

-a_MTBLS9200_LC-MS_negative_reverse-phase_metabolite_profiling.txt  pairing between sample names and filenames in TCA cycle intemedier determination

-s_MTBLS9200.txt contains sample name, cultivation batch, replicate number, genotype pairing for all the deposited data

- m_MTBLS9200_FIA-MS_negative__metabolite_profiling-1_v2_maf.tsv: metabolite IDs and metabolite intensity data of untargeted metabolome measurements

- m_MTBLS9200_LC-MS_alternating_hilic_metabolite_profiling_v2_maf.tsv: metabolite IDs and metabolite intensity data of amino acid measurements

- m_MTBLS9200_LC-MS_negative_reverse-phase_metabolite_profiling_v2_maf.tsv: metabolite IDs and metabolite intensity data of TCA cycle intemedier measurements

The following files contain the same data in a more human-readable format:

 - Amino_acid_determination.csv: pairing between sample names, filenames, and strain IDs for the amino acid measurements

- FIA_untargeted_profiling.csv: pairing between sample names, filenames, and strain IDs for the untargeted metabolome measurements

- Tengolics_PNAS_TCA.tsv: pairing between sample names, filenames, strain IDs, and species name for the TCA intermedier measurements