Gene expression of optic nerve head astrocytes in aged and glaucomatous mouse

Microbeads (experimental glaucoma) or saline solution (controls) were injected into right anterior chamber of young adult mice to induce high intraocular pressure in glaucoma group. In addition, 13 week old and 40 week old naïve C57bl/6 mice were also examined. optic nerve head total RNA profiles of 13 week-young, 40-week old naïve mice, saline injected, and microbeads induced ocular hypertension young adult mice were generated by deep sequencing, in triplicate, using Illumina HiSeq2500.