Photoredox Catalyzed Cyclization of Enaminones/Ketene <i>N</i>,<i>S</i>‑Acetals with β‑Ketodinitriles to Access Polysubstituted Pyrroles
收藏NIAID Data Ecosystem2026-05-10 收录
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资源简介：
A facile synthesis of polyfunctionalized pyrroles has been explored via photoredox cascade cyclization of enaminones/ketene N,S-acetals with β-ketodinitriles using eosin Y, CuI, and Ag2CO3 in acetonitrile under blue LED irradiation at room temperature. The present report offers an efficient and straightforward approach to pyrrole-3-carboxylic acids and pyrrole-3-carboxamides with wide substrate scope and functional group tolerance.
创建时间：
2025-09-15
