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Low-level ciprofloxacin resistant Escherichia coli mutants

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NIAID Data Ecosystem2026-03-11 收录
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The effect of a broad range of sub-inhibitory ciprofloxacin concentrations on antibiotic resistance development in Escherichia coli was tested. The emergence of low-level resistance to both ciprofloxacin and other classes of antibiotics, that is both time and concentration dependent was observed. Whole genome sequencing identified a spectrum of single mutations in resistant strains, both previously described and novel.

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2020-03-11
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