Chan-Soo Lee, Chang-Ki Choi, Eun-Young Shin, Martin Alexander Schwartz, Eung-Gook Kim (2011) CIL:26556, Mus musculus, fibroblast. CIL. Dataset

To study the molecular mechanism by which nonmuscle myosin II (MII) regulates protrusion and adhesion dynamics in migrating cells, NIH3T3 cells were treated with DMSO for 15 min. and stained for βPIX (green) and myosin IIA (red). These findings help elucidate a functional link between MII and Rac1/Cdc42 GTPases, which may regulate protrusion/adhesion dynamics in migrating cells. This image is the original data file from Fig. S4, “Potential involvement of βPIX in blebbistatin-induced morphological changes in MII-regulated cell protrusion and adhesion.” J. Cell Biol. 2010. Vol. 190(4):663–674.

为探究非肌肉肌球蛋白II（MII）调节迁移细胞突起和粘附动态的分子机制，NIH3T3细胞经二甲基亚砜（DMSO）处理15分钟后，进行了βPIX（绿色）和肌球蛋白IIA（红色）的染色。这些发现有助于阐明MII与Rac1/Cdc42 GTPase之间的功能联系，该联系可能调节迁移细胞中突起/粘附动态。本图是图S4“βPIX在MII调节的细胞突起和粘附中可能涉及的blebbistatin诱导的形态变化”的原始数据文件。J. Cell Biol. 2010，Vol. 190(4):663–674。