Supporting data for "Cancer genome standards for long-read sequencing using cancer cell line mixtures"
收藏DataCite Commons2026-03-31 更新2026-05-03 收录
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https://gigadb.org/dataset/102811/
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资源简介：
Long read whole genome sequence data was generated using a PromethION from cultured two cell lines representing distinct tumour types (melanoma, COLO829 and breast cancer, HCC1937) and a matched non-tumour cell line for each. We generated experimental DNA mixtures extracted from cancer cell lines and matched normal cell lines to simulate 10 tumour purities (ranging from 0 to 100% tumour content). This resulted in 22 samples which were sequenced using whole genome long read sequencing to a targeted depth of 60x and somatic variants identified. We down-sampled data to explore the optimal read depth for somatic variant detection.
提供机构：
GigaScience Database
创建时间：
2026-03-31
